Kounis syndrome: Allergic angina and allergic myocardial infarction: Review
Turkiye Klinikleri Cardiovascular Sciences, cilt.22, sa.2, ss.253-261, 2010 (Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 22 Sayı: 2
- Basım Tarihi: 2010
- Dergi Adı: Turkiye Klinikleri Cardiovascular Sciences
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.253-261
- Anahtar Kelimeler: Anaphylaxis, Drug hypersensitivity, Mast cells, Myocardial ischemia
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Allergy and immunology are mostly investigating and fundamental provinces of science. Besides their classical presentations, allergic diseases are contributing to pathophysiology of several disorders. One of them is allergic angina and/or allergic myocardial infarction, which is called as the Kounis Syndrome. Kounis syndrome divided into two subgroups: Type 1 and type 2. Type 1 patients have normal coronary arteries and lacking of risk factors for ischemic heart disease and present two different clinical courses: Some of them experience with coronary spasm and angina without elevated levels of cardiac enzymes and troponine. And others, have a more severe course with elevation in cardiac enzymes which may progress to acute myocardial infarction. In patients with Kounis syndrome type 2, there is an underlying coronary disease. Allergic reactions may facilitate plaque erosion and rupture, which is consequence with myocardial infarction. Collaboration with an allergy specialist in the treatment and management of patients with Kounis syndrome is essential. Not only cardiologist also by allergist should follow the patients with diagnosed allergic disease and coronary heart disease, especially in those patients have allergy to foods or bee venoms, namely carrying increased risk for anaphylaxis. Awareness of Kounis syndrome between physicians, who are dealing with cardiovasculary diseases in their daily practice, is important to attain new visions in diagnosis and treatment. Copyright © 2010 by Türkiye Klinikleri.