Evaluating oxygen reserve index-guided oxygenation for the prevention of postoperative delirium in elderly patients: a randomized controlled trial
Croatian Medical Journal, cilt.66, sa.1, ss.47-55, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 66 Sayı: 1
- Basım Tarihi: 2025
- Doi Numarası: 10.3325/cmj.2025.66.47
- Dergi Adı: Croatian Medical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Central & Eastern European Academic Source (CEEAS), EMBASE, MEDLINE, Directory of Open Access Journals
- Sayfa Sayıları: ss.47-55
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim To assess the effect of oxygen reserve index (ORi)-guided titration of fraction of inspired oxygen (FiO2 ) on the incidence of postoperative delirium (POD) and the frequency of hyperoxemia episodes, assuming a potential link between hyperoxemia and POD. Methods This randomized controlled trial included 114 patients aged 65 years and older, scheduled for elective surgeries lasting over two hours at Health Sciences University Tepecik Training and Research Hospital between Oc-tober 1, 2023, and July 7, 2024. Patients were randomized into the control group (n = 57) or the ORi + pulse oximetry (SpO2 ) group (n = 57). In the ORi+SpO2 group, we dynami-cally adjusted FiO2 based on the real-time ORi and SpO2 values, targeting 95%