Warfarin-induced skin necrosis after open heart surgery due to protein S and C deficiency
Heart and Vessels, cilt.22, sa.1, ss.64-66, 2007 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22 Sayı: 1
- Basım Tarihi: 2007
- Doi Numarası: 10.1007/s00380-006-0935-z
- Dergi Adı: Heart and Vessels
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.64-66
- Anahtar Kelimeler: coronary artery bypass graft surgery, blood, anticoagulation, surgery, complications
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Warfarin-induced skin necrosis is the rare but potentially devastating complication of anticoagulant therapy and commonly occurs in previously undetected C- and S-protein deficient patients. Because routine preoperative examination does not include protein C and S level measurement, detection of these patients preoperatively is generally not possible, which increases the risk of occurrence of this important complication. In this report we present and discuss such a patient, who died from warfarin-induced skin necrosis after coronary artery bypass surgery. © Springer-Verlag Tokyo 2007.