Amlodipine induced massive ascites, a rare clinical case


Arasan S. N., Yenigun E. C., Cevher S. K., DEDE F.

Iranian Journal of Kidney Diseases, cilt.14, sa.6, ss.517-519, 2020 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 6
  • Basım Tarihi: 2020
  • Dergi Adı: Iranian Journal of Kidney Diseases
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.517-519
  • Anahtar Kelimeler: calcium channel blockers, adverse effects, kidney transplantation, pharmacology, edema, chemically induced, ascitic fluid, physiopathology
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Introduction. Calcium channel blockers (CCBs) are commonly used agents in the treatment of hypertension as part of monotherapy or combination therapy. Peripheral edema is the most common side effect that requires discontinuation or replacement of treatment. Some studies in the literature have shown that long-acting dihydropyridine type CCBs lead chylous ascites in peritoneal dialysis patients. However, amlodipine-associated serous ascites cases are not available in the literature. Case Report. In this case report, we describe a rare case of amlodipine induced massive ascites in a 30-year-old male with renal transplantation. Conclusion. We aimed to create awareness that pharmacologic causes should be considered in cases of ascites of unknown aetiology.