Incidentally detected nonspecific and unusual histopathological findings in childhood appendectomy specimens: A retrospective analysis of 2,633 cases Çocukluk çağı apendektomi örneklerinde tesadüfen saptanan nonspesifik ve olağandışı histopatolojik bulgular: 2633 vakanın retrospektif analizi
Ulusal Travma ve Acil Cerrahi Dergisi, cilt.31, sa.11, ss.1130-1136, 2025 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 11
- Basım Tarihi: 2025
- Doi Numarası: 10.14744/tjtes.2025.64744
- Dergi Adı: Ulusal Travma ve Acil Cerrahi Dergisi
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CINAHL, EMBASE, MEDLINE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.1130-1136
- Anahtar Kelimeler: Appendicitis, fibrous obliteration, enterobiasis, carcinoid tumor, serous appendicitis
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
BACKGROUND: Acute appendicitis is an important clinical condition that usually occurs as a result of obstruction of the appendix lumen due to fecaloma or reactive lymphoid hyperplasia. However, in rare cases, various nonspecific and unusual pathologies can cause acute appendicitis or mimic this clinical condition. This study aimed to present patients who underwent surgery with a preliminary diagnosis of acute appendicitis and to determine the frequency of incidentally diagnosed nonspecific and unusual pathologies identified during histopathological examination of the specimens. METHODS: Data from 2,633 patients who underwent appendectomy with a preliminary diagnosis of acute appendicitis in our clinic between January 2014 and June 2023 were retrospectively analyzed. Patients who underwent elective appendectomy in conjunction with other intra-abdominal operations were excluded. Specimens with unusual diagnoses were re-evaluated histopathologically. Data were analyzed statistically. RESULTS: A total of 2,633 patients were included in the study, comprising 1,617 (61.4%) males and 1,016 (38.6%) females. The mean age was 11.32±3.66 years (range: 1-18). All patients underwent a standard appendectomy procedure. Histopathological examination revealed inflamed appendicitis in 2,150 cases (81.65%), perforated appendicitis in 162 cases (6.15%), fibrous obliteration in 104 cases (3.94%), and unusual histopathological findings in 57 cases (2.16%). Of the patients with unusual histopathological findings, 40 were female and 17 were male. Enterobius vermicularis was detected in 41 patients (1.55%), appendicular carcinoid tumor in 10 patients (0.4%), and serous appendicitis in six patients (0.2%). Microscopic findings of acute appendicitis were not observed in 35 of these patients. CONCLUSION: Nonspecific and unusual histopathological findings are more common in childhood appendectomy specimens than in those from adults. Careful histopathological evaluation of appendix specimens allows early diagnosis and treatment of these rarely encountered pathologies.