An experimental study on the comparison of the effects of triester glycerol oxide on wound repair


Sezgin S., Sencimen M., Gülses A., Erdemci F., Ayna M., Gider İ. K., ...Daha Fazla

Oral and Maxillofacial Surgery, cilt.20, sa.3, ss.273-279, 2016 (Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s10006-016-0566-1
  • Dergi Adı: Oral and Maxillofacial Surgery
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.273-279
  • Anahtar Kelimeler: Hydroxyproline, Triester glycerol oxide, Wound, Epithelization
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Aim: The aim of this study is to assess the effects of triester glycerol oxide (TGO) on cutaneous wound epithelization process. Material and methods: Fifty-four male Wistar rats were divided into 2 groups of 27 rats each: control(C) and TGO (PX). The groups have been divided into three subgroups which included nine rats each regarding the wound excision on the 3rd, 7th, and 10th days, respectively. The specimens were evaluated according to histological properties and hydroxyproline levels. Results: Seventh day examination showed that PX and control groups present the same score. HP levels in the control group were significantly lower compared to PX groups. Conclusion: TGO have positive effects on wound epithelization process by increased collagen synthesis.