Gastric mixed adeno-neuroendocrine carcinoma with a large cell neuroendocrine component. A case reports
Annali Italiani di Chirurgia, cilt.8, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 8
- Basım Tarihi: 2019
- Dergi Adı: Annali Italiani di Chirurgia
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: Gastric cancer, MANEC, Mixed adenoneuroandocrine cancer
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Digestive system carcinomas containing a neuroendocrine and an exocrine component are classified as mixed adenoneuroendocrine carcinomas(manec), as one of the component represents at least 30% of the whole lesion. We herein aim to contribute to literature by presenting our rare case of gastric manec. A 58-year-old male patient had a 3 cm mass placed in the antrum in his gastroscopy. The biopsy result was signet ring cell carcinoma. After that total gastrectomy with d2 lymph node dissection and roux-en-y oesophagojejunostomy was performed. The histopathology result was signet ring cell and mucinous adenocarcinoma with large cell neuroendocrine carcinoma component(manec). Manec, a rare type of biphasic tumor, usually has a poor prognosis regardless of its stage and location. This behavior is thought to be caused by the neuroendocrine component. It is vital to know the histopathology of the tumor in order to provide certain standards diagnosis and treatment management.