Thyroid Follicular Carcinoma with Iodine-Avid Bone Metastases Showing Mild Uptake on Both 18F-FDG and 68Ga-DOTATOC PET/CT
Thyroid and Parathyroid Diseases: A Case-Based Guide, Springer International Publishing Ag, ss.347-352, 2018
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2018
- Doi Numarası: 10.1007/978-3-319-78476-2_55
- Yayınevi: Springer International Publishing Ag
- Sayfa Sayıları: ss.347-352
- Anahtar Kelimeler: 18F-FDG PET/CT, Bone metastasis, Differentiated thyroid carcinoma, Radioiodine, Somatostatin receptor imaging
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Differentiated thyroid carcinoma (DTC) is usually characterized by good prognosis. Radioiodine scan is the first-line diagnostic tool to detect the metastatic disease. In patients with high Tg levels suggesting metastatic disease when radioiodine scan is negative, 18F-fluorodeoxyglucose positron emission tomography/computerized tomography (FDG PET/CT) is reported to be effective in defining the metastatic foci. Another imaging modality is somatostatin receptor imaging with PET/CT which can be used especially when 18F-FDG PET/CT is nondiagnostic. Peptide receptor radionuclide therapy with β-emitting radionuclides may be considered when somatostatin positivity is defined in metastatic lesions. In this case report, a patient with DTC having radioiodine-positive bone metastases showing mild uptake in 18F-FDG PET/CT and 68Ga-DOTATOC PET/CT is presented.