Tp–e interval and Tp–e/QT ratio in patients with Human Immunodeficiency Virus
Journal of Infection and Public Health, cilt.11, sa.1, ss.35-38, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 11 Sayı: 1
- Basım Tarihi: 2018
- Doi Numarası: 10.1016/j.jiph.2017.02.008
- Dergi Adı: Journal of Infection and Public Health
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.35-38
- Anahtar Kelimeler: Human Immunodeficiency Virus, Tp-e interval, Tp-e/QT ratio
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Human Immunodeficiency Virus (HIV) infection and AIDS are known to cause cardiovascular diseases such as premature coronary artery disease, cardiomyopathy, and arrhythmias. Recently, Tp–e interval and Tp–e/QT ratio has been shown as a novel marker of ventricular repolarization. We aimed to evaluate the ventricular repolarization using Tp–e interval and Tp–e/QT ratio in patients with Human Immunodeficiency Virus (HIV) infection. Totally 48 patients with HIV and 60 control subjects were enrolled to the study. Tp–e interval, Tp–e/QT and Tp–e/QTc ratio were measured from the 12-lead electrocardiogram. Tp–e interval, Tp–e/QT ratio and Tp–e/QTc ratio were significantly higher in patients with HIV than control subjects (all p < 0.01). In correlation analysis, there were positive correlation between Tp–e interval and disease duration (r = 0.298, p = 0.048). and inverse correlation between Tp–e interval and CD4 count(r = −0.303, p = 0.036). Our study showed that Tp–e interval, Tp–e/QT and Tp–e/QTc ratios were increased in patients with HIV than control subjects.