Effects of maternal smoking on fetal organs
Advances in Clinical and Experimental Medicine, cilt.21, sa.4, ss.441-446, 2012 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 4
- Basım Tarihi: 2012
- Dergi Adı: Advances in Clinical and Experimental Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.441-446
- Anahtar Kelimeler: cigarette smoking, lung, apoptosis
- Sağlık Bilimleri Üniversitesi Adresli: Hayır
Özet
Background. Unfavorable effects of in-utero smoke exposure have been shown in several studies. Objectives. In this experimental study, the authors aimed at showing detrimental effects of cigarette smoke on fetal tissues by assessing apoptosis that is detected by performing TUNEL staining. Material and Methods. Designed groups were smoke exposed rats before and during pregnancy and control groups. Rat offsprings were sacrificed when they were 12 days old. Results. Lung, kidney, adrenal and gonad tissues were harvested for histopathologic analysis and assessed by TUNEL (Terminal dUTP Nick End Labeling) staining. Conclusions. Smoke exposure caused increased apoptotic activity in lung parenchyma of study groups.