Evaluation of HSP70 levels in ectopic pregnancy, abortus imminens and intrauterine pregnancy
Biomarkers in Medicine, cilt.16, sa.18, ss.1251-1258, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 16 Sayı: 18
- Basım Tarihi: 2022
- Doi Numarası: 10.2217/bmm-2022-0550
- Dergi Adı: Biomarkers in Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, EMBASE, MEDLINE
- Sayfa Sayıları: ss.1251-1258
- Anahtar Kelimeler: abortus imminens, biomarker, ectopic pregnancy, heat shock protein, HSP70, pregnancy, pregnancy of unknown location
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: To assess the serum levels of HSP70 concentrations in ectopic pregnancy (EP) patients compared with abortus imminens (AI) patients and healthy controls. Materials & methods: Age-matched patients were divided into three groups, with 30 patients in each group: EP, AI and healthy intrauterine pregnancy groups. Blood samples were taken from the antecubital vein and kept for HSP70 analysis. Results: The HSP70 levels were higher in the EP group than in AI patients and healthy controls (p < 0.05). The area under the curve for the serum HSP70 assay reached a value of 0.81 for a cutoff point of 11.12 pg/ml, which identified women with EP. Conclusion: Serum HSP70 levels increased in women with EP compared with healthy controls and women with AI.