Prognostic significance of the HALP score in patients with acute ischemic stroke
Postgraduate Medical Journal, cilt.102, sa.1205, ss.283-289, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 102 Sayı: 1205
- Basım Tarihi: 2026
- Doi Numarası: 10.1093/postmj/qgaf225
- Dergi Adı: Postgraduate Medical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Health Research Premium Collection (ProQuest)
- Sayfa Sayıları: ss.283-289
- Anahtar Kelimeler: Acute ischemic stroke, HALP score, prognosis, mortality
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aim: To investigate the relationship between the Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score and prognosis in patients with acute ischemic stroke (AIS). Methods: This retrospective, cross-sectional, observational, single-center study enrolled 1128 patients with AIS who presented to the emergency department and were hospitalized between June 2019 and December 2021. The HALP score was calculated as follows: hemoglobin (g/L) × albumin (g/L) × lymphocytes (/L)/platelets (/L). Demographics, clinical characteristics, and HALP scores were compared between survivors and nonsurvivors to identify factors associated with in-hospital mortality. Results: The HALP scores for nonsurvivors and survivors were 13.9 [7.2–25.9] and 36.4 [22.8–52.8], respectively. Compared to the survivors, the HALP score was significantly lower in nonsurvivor patients. Conclusions: The HALP score has prognostic value in patients with AIS. Patients with lower HALP scores at admission are at higher risk for prolonged hospital stay, need for intensive care, and mortality, suggesting that a low score may be predictive of poor prognosis in patients with AIS. The cut-off value for predicting mortality was 21.5.