Microsurgical Anatomy of the Insular Region and Its Connections: A Fiber Dissection Study İnsular Bölgenin ve Bağlantılarının Mikrocerrahi Anatomisi: Bir Fiber Diseksiyon Çalışması
Medical Journal of Bakirkoy, cilt.21, sa.4, ss.449-457, 2025 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 21 Sayı: 4
- Basım Tarihi: 2025
- Doi Numarası: 10.4274/bmj.galenos.2025.2025.1-15
- Dergi Adı: Medical Journal of Bakirkoy
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.449-457
- Anahtar Kelimeler: Insula, fiber dissection, neurosurgery, neuroanatomy
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: The insular cortex is a structurally complex and functionally significant brain region, influencing a wide range of neurophysiological processes, including autonomic regulation and emotional cognition. This study aims to provide a detailed analysis of the microsurgical anatomy of the insula and its intricate white matter connections through meticulous fiber dissections of postmortem human brains. Methods: Four postmortem human brains were preserved in a 10% formalin solution for at least two months. After removing the arachnoid mater, pia mater, and vascular structures, the brains were frozen at -16 °C for at least two weeks. Following rehydration in a 70% alcohol solution at room temperature, white matter dissections were performed using the Klingler technique. Results: Dissection of the frontal, parietal, and temporal opercula revealed the insula, characterized by an inverted pyramidal shape at the base of the Sylvian fissure. The limen insula, an important anatomical landmark situated deep within the Sylvian fissure, was identified as a crucial reference point in surgical procedures. Upon removal of the insular cortex, detailed structural relationships between the insula, basal ganglia, and white matter tracts were demonstrated. Conclusion: This study highlights the necessity of advanced surgical precision in addressing insular pathologies to improve neurosurgical outcomes.