Mitochondrial transplantation, methods and mitochondrial dysfunction related diseases: An overview
Mitochondrial Transplantation and Transfer: Biology, Methods, Applications, and Disease, Elsevier, ss.3-15, 2024
- Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
- Basım Tarihi: 2024
- Doi Numarası: 10.1016/b978-0-443-18858-9.00001-9
- Yayınevi: Elsevier
- Sayfa Sayıları: ss.3-15
- Anahtar Kelimeler: Mitochondria, Mitochondria transfer, Mitochondrial diseases, Mitochondrial transplantation, Mitochondrial transplantation techniques
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Mitochondria are fundamental organelles to cell function. Mitochondrial functions include not only energy production but also a variety of other crucial processes that are all necessary for sustaining homeostasis. They are endosymbiotic organelles with two protective membranes and partial independence from the cell nucleus. Because of these qualities, mitochondria are known as transferable organelles. During physiological processes, cells exchange mitochondria with one another, and foreign mitochondria can be implanted into a cell. Aside from this, foreign mitochondria can be transplanted artificially, a process known as mitochondrial transplantation. The interest in this area of research has attracted many scientists. Research topics include, but are not limited to, diseases associated with mitochondrial DNA damage or mitochondrial dysfunction. This chapter provides an overview of several subjects, including the features and functions of the mitochondria organelle, mitochondria transfer in physiological processes, methods and areas of research on mitochondrial transplantation, as well as the findings of these studies.