Lympho-vascular space invasion indicates advanced disease for uterine papillary serous tumors arising from polyps
Asian Pacific Journal of Cancer Prevention, cilt.16, sa.10, ss.4257-4260, 2015 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 16 Sayı: 10
- Basım Tarihi: 2015
- Doi Numarası: 10.7314/apjcp.2015.16.10.4257
- Dergi Adı: Asian Pacific Journal of Cancer Prevention
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.4257-4260
- Anahtar Kelimeler: LVSI, Myometrial, Polyp, Serous, Uterine cancer
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Background: Uterine papillary serous tumors are rarely seen and behave aggressively. Our aim was to evaluate uterine papillary serous tumors arising from polyps. Materials and Methods: Clinicopathological data of patients with uterine serous cancer arising from a polyp at the Gynecological Oncology Department of Zekai Tahir Burak Women's Health Education and Research Hospital were reviewed retrospectively. Results: We analyzed patients according to FIGO 2009 staging system as stage 1A and higher than stage 1A (3 and 6, respectively). All the patients were postmenopausal. Mean CA-125, CA-19.9 and CA15.3 levels were elevated in higher than stage 1A group. However we did not find a statistical difference between age, parity, polyp size, CA-125, CA-15.3, CA-19.9 and CEA levels. Lympho-vascular space invasion (LVSI) showed predictivity for advanced disease (p=0.025). Conclusions: The histopathologic nature of uterine serous carcinoma is a unique entity. LVSI is a prognosticator for defining an advanced stage uterine papillary tumor.