Systemic sarcoidosis induced by chemotherapy, mimicking metastatic testicular carcinoma with18F-FDG PET/CT 18 F-FDG PET/BT görüntülemede metastatik testis karsinomunu taklit eden kemoterapi tedavisinin indüklediği sistemik sarkoidoz


ARSLAN E., Aksoy T., Ekemen S., Çermik T. F.

Molecular Imaging and Radionuclide Therapy, cilt.30, sa.2, ss.126-128, 2021 (ESCI, Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 2
  • Basım Tarihi: 2021
  • Doi Numarası: 10.4274/mirt.galenos.2020.51422
  • Dergi Adı: Molecular Imaging and Radionuclide Therapy
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.126-128
  • Anahtar Kelimeler: Systemic sarcoidosis, testis carcinoma, F-18-FDG PET/CT
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

A 34-year-old male patient who had left orchiectomy and received three cycles of chemotherapy for testicular mix germ cell carcinoma was referred for18fluorine-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) for complaints of weight loss and fever. PET/CT showed multiple and progressive18F-FDG uptakes in supra and infra diaphragmatic lymphatic regions, and multiple abnormal 18 F-FDG uptakes were noted in the lytic formed skeletal lesions. Clinicians remain in doubt regarding the multiple metastatic lesions without elevated serum tumor marker levels (alpha-fetoprotein, beta-human chorionic gonadotrophin, CA19-9, and carcinoembryonic antigen). Biopsy of the lytic lesion in the iliac bone revealed granulomatous inflammation suggestive of sarcoidosis. Systemic prednisone at 20-40 mg/daily was started.18F-FDG PET/CT images showed complete metabolic response to prednisone 8 months following the start of treatment.