Evaluation of Eosinophil-to-Lymphocyte Ratio and Eosinophil Count as Predictive Markers in Fibromyalgia Syndrome
Pakistan Journal of Medical Sciences, cilt.41, sa.7, ss.2087-2091, 2025 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 7
- Basım Tarihi: 2025
- Doi Numarası: 10.12669/pjms.41.7.12064
- Dergi Adı: Pakistan Journal of Medical Sciences
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals
- Sayfa Sayıları: ss.2087-2091
- Anahtar Kelimeler: Fibromyalgia syndrome, Eosinophil-to-lymphocyte ratio, Inflammation, Hemogram
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: This study aimed to investigate the predictive role of eosinophil-to-lymphocyte ratio (ELR), and eosinophil count (EC) in patients with Fibromyalgia syndrome (FMS) and to compare with healthy controls. Method: This retrospective observational study was conducted from January 1st to December 31st, 2024 in Konya Beyhekim Training and Research Hospital. 109 FMS (101 female/8 male) patients who met the 2016 American College of Rheumatology (ACR) classification criteria and 85 (75 female/10 male) healthy controls were included in the study. Demographic characteristics, neutrophil, lymphocyte, and eosinophil counts (EC) levels were recorded. ELR, neutrophil-lymphocyte ratio (NLR) calculated. Results: In patients with FMS, the blood ELR, NLR, and EC were significantly higher compared to the control group (p<0.05). In the roc curve analysis, blood NLR had 62.4% sensitivity and 50% specificity; blood ELR and EC ≥had 60.6% sensitivity but < 40 % specificity in predicting fibromyalgia. Conclusion: The results of this study showed that ELR and EC are promising inflammatory markers in the diagnosis of fibromyalgia and should be evaluated in a larger population along with other hemogram parameters.