The role of gastric Helicobacter pylori infection in laryngopharyngeal reflux disease
Otolaryngology - Head and Neck Surgery, cilt.135, sa.1, ss.52-55, 2006 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 135 Sayı: 1
- Basım Tarihi: 2006
- Doi Numarası: 10.1016/j.otohns.2006.03.020
- Dergi Adı: Otolaryngology - Head and Neck Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.52-55
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objectives: To investigate the role of Helicobacter pylori (H pylori) infection in laryngopharyngeal reflux (LPR). Study design: A prospective multidisciplinary clinical study. Methods: Forty-four adult patients who applied to our ENT clinic with LPR symptoms were evaluated. Then these patients underwent upper gastrointestinal system endoscopy and double probe pH monitoring. In addition, during the endoscopy multiple biopsies from the stomach were obtained to detect H pylori. Results: Results from 32 LPR positive patients were assessed (10 male and 22 female). There were no statistically significant differences between the presence of H pylori and sex, age, degree of gastritis and esophagitis, and also the number of reflux, fractional acid exposure time regarding proximal probe readings. Similarly for both proximal and distal probe readings, the average score of esophageal acid clearance was not statistically significant (P > 0.05). In addition, no statistically significant difference was found between the presence of H pylori and GERD (P > 0.05). Conclusions: The results of this study demonstrated that there is no relationship between gastric H pylori infection and LPR. EBM rating: B-3b. © 2006 American Academy of Otolaryngology-Head and Neck Surgery Foundation.