Perinatal outcomes of high-dose vitamin d administration in the last trimester Son trimesterde yüksek doz d vitamini uygulamasının perinatal sonuçları
Turkish Journal of Obstetrics and Gynecology, cilt.18, sa.2, ss.159-162, 2021 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 18 Sayı: 2
- Basım Tarihi: 2021
- Doi Numarası: 10.4274/tjod.galenos.2021.90023
- Dergi Adı: Turkish Journal of Obstetrics and Gynecology
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.159-162
- Anahtar Kelimeler: Hypercalcemia, 25 (OH) vitamin D, vitamin D intoxication, neonatal outcomes
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
In recent years, interest in the evaluation of vitamin D levels and the possible outcomes of their deficiency during pregnancy has increased. However, there is no consensus on when to start vitamin D supplementation, its duration, dosage, and the optimum level during pregnancy. The toxicity of vitamin D is as important as its deficiency. From the history of a 5-day-old male baby who was investigated for hypercalcemia, it was learned that the mother took 300,000 IU vitamin D-five ampoules/oral at 30 weeks of gestation every other day. The infant was born prematurely, postpartum bradycardia required positive pressure ventilation, and his hypercalcemia lasted approximately 4 months despite treatment. Maternal excessive and inappropriate use of vitamin D can cause preterm labor and severe hypercalcemia, which is a life-threatening complication in the neonatal period. This case is presented to draw attention to the negative effects of maternal high-dose vitamin D during pregnancy.