The forgotten player of in-stent restenosis: Endothelial dysfunction


Celik T., Iyisoy A., Kursaklioglu H., ÇELİK M.

International Journal of Cardiology, cilt.126, sa.3, ss.443-444, 2008 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 126 Sayı: 3
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.ijcard.2007.02.050
  • Dergi Adı: International Journal of Cardiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.443-444
  • Anahtar Kelimeler: in-stent restenosis, endothelial dysfunction
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Reduced coronary endothelium-dependent vasodilation may play a role in the pathophysiology of in-stent restenosis. Moreover, endothelial dysfunction may cause to progression of athetrosclerosis in coronary arteries in patients undergoing percutaneous coronary intervention, especially stent deployment. We believe that the agents improving endothelial dysfunction and healing-enhanced stents, namely vascular endothelial growth factor (VEGF)-eluting stents, estradiol-eluting stents and stents attracting endothelial cells, might take an important role in the prevention of stent restenosis strategies in the near future. © 2007 Elsevier Ireland Ltd. All rights reserved.