A successful desensitization in an adult patient with ARA-C infusion reaction
Journal of Oncology Pharmacy Practice, cilt.30, sa.4, ss.780-782, 2024 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 4
- Basım Tarihi: 2024
- Doi Numarası: 10.1177/10781552241242691
- Dergi Adı: Journal of Oncology Pharmacy Practice
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.780-782
- Anahtar Kelimeler: Drug allergy, desensitization, ARA-C, cytarabine
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: Cytarabine (ARA-C) is an antimetabolite agent used especially in the treatment of hematologic malignancies. Infusion reactions have an important place among the side effects that may occur due to treatment. Clinical findings of infusion reactions resemble allergic reactions. Case Report: 47-year-old male patient with a diagnosis of B-cell Acute Lymphoblastic Leukaemia developed infusion reaction during ARA-C treatment. Management & Outcome: There was no alternative treatment option for his existing malignant disease, we decided ARA-C desensitization. Discussion: We would like to describe a successful desensitization protocol in an adult patient who experienced a reaction during ARA-C infusion.