Is it possible to estimate the mortality rate of fournier gangrene with new parameters?

KARAALİ C., Salimoglu S., Emiroglu M., Budak G. G., ÇALIK B., AYDIN C.

Kuwait Medical Journal, cilt.52, sa.3, ss.286-290, 2020 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 52 Sayı: 3
  • Basım Tarihi: 2020
  • Dergi Adı: Kuwait Medical Journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Sayfa Sayıları: ss.286-290
  • Anahtar Kelimeler: acute renal failure, Fournier Gangrene, mortality, new parameters, platelet distribution width
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Objective: The aim of the study was to compare currently used parameters and a new parameter platelet distribution width (PDW) to assess its potential value in estimating mortality in patients with Fournier gangrene. Design: Retrospective study Setting: Tepecik Training and Research Hospital, Izmir, Turkey Subjects: Eighty-nine patients diagnosed with Fournier gangrene between January 2006 and March 2017 were included in this study. Interventions: The two groups of patients, survivors and non-survivors, were compared with regard to the demographic data of patients, laboratory parameters, Age Charlson Comorbidity Index (ACCI), Uludag Fournier’s Gangrene Severity Index (UFGSI), Fournier’s Gangrene Severity Index (FGSI), Simplified Fournier’s Gangrene Severity Index (SFGS), the neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio, red cell distribution width (RDW) and PDW. Main outcome measures: Mortality rate of Fournier Gangrene Results: There was a statistically significant correlation between mortality and ACCI, UFGSI, FGSI, SFGS, NLR and RDW. Advanced age, low calcium level, hemoglobin, haematocrit, bicarbonate levels and high levels of blood urea nitrogen were found to be significant factors for mortality (P<.05). Conclusions: Our results revealed that ACCI, UFGSI, FGSI, SFGS, NLR and PDW are reliable predictors of mortality in patients with Fournier gangrene. Simple to calculate parameters such as SFGSI, NLR and PDW are helpful in predicting mortality in daily practice.