Neurochemical markers during selective cerebral perfusion via the right brachial artery
Interactive Cardiovascular and Thoracic Surgery, cilt.10, sa.6, ss.948-952, 2010 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 10 Sayı: 6
- Basım Tarihi: 2010
- Doi Numarası: 10.1510/icvts.2009.228858
- Dergi Adı: Interactive Cardiovascular and Thoracic Surgery
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.948-952
- Anahtar Kelimeler: Aortic arch, Cerebral protection, Neurological injury
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Unilateral selective cerebral perfusion through right brachial artery is one of the cerebral protection methods for aortic arch repair. The purpose of this study is to determine whether cerebral perfusion through contra-lateral hemisphere is adequate or not. Seventeen consecutive patients underwent aortic arch repair using low flow antegrade selective cerebral perfusion (ASCP) through right brachial artery under moderate hypothermia. We measured S100β and neuron-specific enolase (NSE) levels, venous O2 saturation, lactate, and glucose from both left and right jugular vein blood samples before, during and following ASCP and cardiopulmonary bypass. There was no operative mortality or neurological complication in these patients. No significant differences were observed in S100β and NSE levels, venous saturation, glucose and lactate between the blood samples which were gathered from both jugular veins, statistically. This technique, as far as biochemical markers are concerned, seems to provide adequate perfusion for both right and left cerebral hemispheres. © 2010 Published by European Association for Cardio-Thoracic Surgery. All rights reserved.