Body mass index and ghrelin levels after laparoscopic nissen fundoplication
Langenbeck's Archives of Surgery, cilt.400, sa.5, ss.585-588, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 400 Sayı: 5
- Basım Tarihi: 2015
- Doi Numarası: 10.1007/s00423-015-1315-x
- Dergi Adı: Langenbeck's Archives of Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.585-588
- Anahtar Kelimeler: BMI, Ghrelin, Nissen fundoplication
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Purpose The study aims to evaluate the changes between body mass index (BMI) and ghrelin levels after laparoscopic Nissen fundoplication (LNF). Methods Twenty-four consecutive patients with gastroesophageal reflux disease who were scheduled for LNF consented to participate in the study. The participants’ age, sex, preoperative (phase 0), postoperative 1st week (phase 1) and postoperative 4th week (phase 2) dysphagia scores, plasma ghrelin levels, and BMI were recorded. Results Compared to the preoperative level (phase 0), ghrelin was decreased in both phase 1 and phase 2. A strong correlation in the changes in the ghrelin values and BMI between phase 0 and phase 2 was detected. There was a strong, statistically significant difference in the changes in the BMI values between phase 1 and phase 2. Conclusions Total plication of the fundus impairs its ghrelinsecreting functions for up to 4 weeks and is accompanied by weight loss.