The effects of pharmacomechanical thrombectomy on novel complete blood count parameters in deep vein thrombosis: A retrospective study

YENER A. Ü., YALÇINKAYA A., Yener Ö., Çelik E. C., Hanedan O., ÇİÇEK M. C., ...Daha Fazla

Medicine (United States), cilt.102, sa.7, 2023 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 102 Sayı: 7
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1097/md.0000000000033008
  • Dergi Adı: Medicine (United States)
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, CINAHL, Veterinary Science Database, Directory of Open Access Journals
  • Anahtar Kelimeler: catheter-based interventions, deep vein thrombosis, mechanical thrombectomy, neutrophil-lymphocyte ratio, platelet-lymphocyte ratio
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

This study aimed to investigate the effects of pharmacomechanical thrombectomy on novel complete blood count parameters in deep venous thrombosis. This retrospective study included 242 patients aged >18 years who were treated for deep venous thrombosis. Patients were grouped as follows: group 1 was accepted as having interventional operations (n = 123) and group 2 was accepted as having only medical advice (n = 119). Routine complete blood count parameters, the neutrophil-to-lymphocyte ratio (NLR), and the platelet-to-lymphocyte ratio (PLR) were compared. There was no difference between the groups in terms of admission hemoglobin, hematocrit, mean platelet volume, NLR and PLR (P =.11, P =.24, P =.55, P =.93, and P =.96, respectively). In the pharmacomechanic thrombectomy group, NLR and PLR were significantly reduced after intervention when compared to the admission values (P <.001 and P <.001, respectively). However, the NLR and PLR values of medically treated patients did not differ significantly from their baseline values (P =.16 and P =.08, respectively). In this study, we effectively removed the thrombus load in blocked proximal veins using pharmacomechanical thrombectomy and observed a significant decrease in NLR and PLR, which are current, inexpensive, and accessible parameters.