Influence of smoking on serum and milk of mothers, and their infants' serum insulin-like growth factor-I and insulin-like growth factor binding protein-3 levels
Hormone Research, cilt.62, sa.6, ss.288-292, 2004 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 62 Sayı: 6
- Basım Tarihi: 2004
- Doi Numarası: 10.1159/000081974
- Dergi Adı: Hormone Research
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.288-292
- Anahtar Kelimeler: smoking, pregnancy, milk, human, insulin-like growth factor-I, insulin-like growth factor binding protein-3
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: To investigate the serum and milk in active-smoking and nonsmoking mothers, and their infants' insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) levels. Design and Setting: A cohort study conducted at a tertiary medical center. Subjects: Forty-four mothers (age range: 21-34 years) and their newborns (7 days old) were enrolled in the study. Mothers were interviewed and classified according to their smoking status into one of two groups: the active-smoking mothers (n = 21) and the nonsmoking mothers (n = 23). Results: There was no difference noted in either IGF-I, IGFBP-3 or IGF-I/IGFBP-3 ratios in serum and milk of mothers, and their infants' serum samples according to maternal smoking. Conclusion: This study demonstrated that maternal smoking (5-10 cigarettes/day) did not influence the maternal and infant serum levels of IGF-I and IGFBP-3 as well as the breast milk levels of these peptides. Copyright © 2004 S. Karger AG, Basel.