Long-term outcomes of augmentation cystoplasty: A retrospective view of 54 children Resultados a largo plazo de la cistoplastia de ampliación: una evaluación retrospectiva de 54 niños
Actas Urologicas Espanolas, cilt.46, sa.8, ss.487-493, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 46 Sayı: 8
- Basım Tarihi: 2022
- Doi Numarası: 10.1016/j.acuro.2021.12.007
- Dergi Adı: Actas Urologicas Espanolas
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Gender Studies Database, MEDLINE, DIALNET
- Sayfa Sayıları: ss.487-493
- Anahtar Kelimeler: Bladder augmentation, Congenital urinary defects, Vesical exstrophy, Spinal dysraphism, Posterior urethral valve, Mitrofanoff
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction and objectives: Throughout the years, clinicians dealing with pediatric urology disorders have resorted to bladder augmentation (BA), a demanding surgical procedure, to preserve renal functions in sundry congenital urinary tract defects. This study aimed to reveal the very long-term outcomes of BA in a large sample of pediatric patients and the role of underlying disease on renal prognosis after BA. Materials and methods: A retrospective cross-sectional study was conducted on 54 children with congenital urinary defects who underwent BA. The utilized augmentation technique, the location of ureter implantation, complications, and ultrasonography findings were analyzed. Data on serum creatinine levels were collected from preoperative records and anniversaries following BA. Results: Among 54 children, 33 (61.1%) were boys. Diagnoses were spinal dysraphism (SD) (n = 13), posterior urethral valve (PUV) (n = 8), bladder exstrophy (n = 32) and trauma (n = 1). The median follow-up duration was 18 (3-31) years. The comparisons of serum creatinine levels between groups revealed that, despite no meaningful difference was present between bladder exstrophy and PUV group in the preoperative period and postoperative 1st year, cases with PUV had significantly higher levels of serum creatinine levels in the following postoperative years. Therewithal compared with the SD group, subjects with PUV had significantly higher levels at the postoperative 2nd year (P = .035) and 10th year (P = .006). Conclusions: In our study, significantly long-term follow-up outcomes could facilitate the pre- and postoperative approach for enterocystoplasty in children. According to our results, it is noteworthy that kidney functions are at high risk of worsening in subjects with PUV and underwent BA.