Postoperative pancreatic fistula: Low preoperative ejection fraction may be another contributing factor
Kuwait Medical Journal, cilt.54, sa.3, ss.320-326, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 54 Sayı: 3
- Basım Tarihi: 2022
- Dergi Adı: Kuwait Medical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Sayfa Sayıları: ss.320-326
- Anahtar Kelimeler: ejection fraction, pancreaticoduodenectomy, postoperative pancreatic fistula
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: We investigated if ejection fraction (EF) was a predisposing factor for postoperative pancreatic fistula (POPF) as a perfusion indicator, or not. Design: This was a retrospective single center study. Setting: Türkiye Yüksek İhtisas Training and Research Hospital, Clinic of Gastroenterologic Surgery, Ankara, Turkey Subjects: A total of 77 patients who underwent pancreaticoduodenectomy Intervention: EF values were divided into three groups with demographic similarity as 40-49, 50-59, and 60 and above. The relationship between EF and POPF was investigated. Main outcome measures: Preoperative EF, albumin, bilirubin, hemoglobin, C-reactive protein, white blood cells, neutrophil, lymphocyte, aspartate aminotransferase, alanine transaminase, gamma glutamyl transferase, carcinoembryonic antigen, CA19-9 values; intraoperative data such as operation type, ductus diameter in pancreas after resection, the presence of porta resection; postoperative pathology results, fistula grades, and 1st and 3rd day drain and blood amylases were retrospectively recorded. Results: EF value was found to be between 40-49 in 10 (13%) patients, between 50-59 in 37 (48%) patients, and 60 or above in 30 (39%) patients. EF values of cases with leakage were found to be statistically significantly lower than the cases without leakage (P <0,05). In case of leakage, optimal cut-off value was calculated as ≤52. Conclusion: EF values of cases with leakage in pancreas fistulas were found to be statistically significantly lower than the cases without leakage (P <0.05). Cut-off value was found as 52 (area under curve, with 93% interval of confidence). EF value below 52 in patients who underwent pancreaticoduodenectomy statistically increases pancreatic fistulas.