Gastroesophageal Reflux Disease

Kırık, Mehtap; Coskun, Berna

doi:10.1007/978-3-031-22483-6_133-1

Gastroesophageal Reflux Disease

Kırık M. O., Coskun B. U.

Airway Diseases: Volume 1-3, Springer International Publishing Ag, ss.2495-2521, 2023

Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
Basım Tarihi: 2023
Doi Numarası: 10.1007/978-3-031-22483-6_133-1
Yayınevi: Springer International Publishing Ag
Sayfa Sayıları: ss.2495-2521
Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Gastroesophageal reflux disease (GERD) is a common motility disorder of the upper gastrointestinal tract characterized by the retrograde movement of gastric contents into the esophagus, leading to chronic symptoms and/or tissue damage and negatively affecting the quality of life. GERD can be seen in all age groups, and its prevalence may vary in different populations. In the pathophysiology of GERD, there are many causes, such as lower esophageal sphincter/esophagogastric junction diseases, delayed emptying of gastric contents, acid pocket, hiatal hernia, impaired mucosal defense mechanisms of the esophagus, and decreased salivary function. These causes indicate that cellular/biochemical deterioration is also involved in the pathophysiology of GERD, in addition to the deterioration in tissue anatomy. Although the first step of the diagnosis is the history of symptoms, the diagnosis may not always be made easily, and some cases may require various advanced diagnostic methods. A patient-specific treatment and follow-up are required for GERD, as it negatively affects the patient's quality of life and may cause premalignant esophageal complications. Symptoms can be controlled in many patients by modifying their lifestyle and preferring various pharmacologic agents when necessary. However, in patients with advanced GERD for whom medical treatment options are insufficient, appropriate surgical options should be considered in order to prevent and treat GERD complications. It should be known that patients with GERD may present with extraesophageal complications such as chronic cough, laryngitis, and dental problems. Therefore, a multidisciplinary approach is required for patients with GERD.