The relationship between Vitamin D levels and nondipper hypertension
Blood Pressure Monitoring, cilt.20, sa.6, ss.330-334, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 20 Sayı: 6
- Basım Tarihi: 2015
- Doi Numarası: 10.1097/mbp.0000000000000146
- Dergi Adı: Blood Pressure Monitoring
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.330-334
- Anahtar Kelimeler: dipper hypertension, nondipper hypertension, vitamin D
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective Nondipper hypertension is associated with increased cardiovascular morbidity and mortality. Vitamin D deficiency is associated with cardiovascular diseases such as coronary artery disease, heart failure and hypertension. We aimed to evaluate the effect of vitamin D on nondipper hypertension. Design This study included total 200 essential hypertensive patients. Twenty-four-hour ambulatory blood pressure monitoring was performed for each patient. In addition to routine tests, vitamin D levels were analysed. Results The study population was divided into two groups: 100 dipper patients (mean age; 50.6 ± 9.9 years, 54 women and 46 men) and 100 nondipper patients (mean age; 49.2± 8.2 years, 53 women and 47 men). Clinical blood pressures were significantly higher in nondipper hypertensives than dipper hypertensives (systolic blood pressures 141.2 ±5.6 vs. 139.1± 6.6 mmHg, diastolic blood pressures 88.4± 2.6 mmHg vs. 87.4± 3.4, P<0.05, respectively). Nondipper patients showed lower levels of vitamin D compared with dippers (21.1± 3.5, 31± 7.1 ng/ml, P<0.001, respectively). A significant positive correlation was observed between vitamin D and the rate of nocturnal systolic and diastolic blood pressure fall (r=0.525, P<0.001 and r=0.512, P<0.001, respectively) Conclusion Vitamin D levels are significantly lower in patients with nondipper hypertension than patients with dipper hypertension.