C-Reactive Protein to Albumin Ratio in Patients With Saphenous Vein Graft Disease


YAYLA Ç., Gayretli Yayla K.

Angiology, cilt.72, sa.8, ss.770-775, 2021 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 72 Sayı: 8
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1177/0003319721998863
  • Dergi Adı: Angiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, Food Science & Technology Abstracts, MEDLINE
  • Sayfa Sayıları: ss.770-775
  • Anahtar Kelimeler: C-reactive protein to albumin ratio, inflammation, saphenous vein graft disease, SYNTAX score
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Atherosclerosis plays an important role in saphenous vein graft disease (SVGD). Previous studies showed that inflammatory blood cells play an active role in this process. C-reactive protein to albumin ratio (CAR) is considered as a novel predictor for cardiovascular risk and an indicator of inflammation. We aimed to assess the relationship between SVGD and CAR. A total of 711 participants with saphenous vein graft (SVG) were included; 348 patients had SVGD and 363 patients had patent (no stenosis) SVG. C-reactive protein to albumin ratio was higher in patients with SVGD (P <.001). There was a significant positive correlation between CAR and the age of SVG (r = 0.123; P =.001) and SYNTAX score (r = 0.568; P <.001). Multivariate logistic regression analyses showed that lymphocyte count, CAR, and SYNTAX score were independent predictors of SVGD (P <.05). C-reactive protein to albumin ratio may be a useful marker after bypass surgery to predict SVGD.