The role of using multimodal imaging and elastography for diagnosing male breast cancer: new challenges and new diagnostic tools
Kuwait Medical Journal, cilt.55, sa.3, ss.205-212, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 55 Sayı: 3
- Basım Tarihi: 2023
- Dergi Adı: Kuwait Medical Journal
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.205-212
- Anahtar Kelimeler: breast, elastography, male breast cancer, multimodal imaging
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objectives: This study evaluates the contribution of imaging modalities for male breast cancer and the initial clinical experience of elastography in male breast cancer. Our research is a unique and a pioneer study in this respect. Design: Prospective study Setting: Department of Radiology, Haseki Training and Research Hospital, Istanbul, Turkey Subjects: Fifteen men who had malign breast lesions were included. Intervention: Mammography, ultrasonography (US) with real-time strain elastography (RTE) and magnetic resonance imaging were performed. Main outcome measures: The lesions were classified into the final Breast Imaging Reporting and Data System category. All patients underwent core-needle biopsies. Results: A total of 17 malignant breast lesions with a mean size of 24.29±12.51 mm were diagnosed on 15 men. The mean age was 62.21±11.00 years (age range: 39-75 years). Fourteen of the 16 solid breast lesions were invasive ductal carcinomas (IDC), one was papillary carcinoma (PC) and one was ductal carcinoma in situ. One patient had bilateral breast cancer: the right breast was IDC, and the left breast was PC. The RTE was performed on only ten patients; elasticity score had two false negatives, although the elasticity index (EI) of two patients was malignant. The EI showed two false-negative results. The elastography’s performance combined with the conventional US had no false-negative result. Conclusion: The multimodality approach leads to a more accurate assessment of male breast cancer. Elastography combined with conventional ultrasound can provide specific benefits and information on breast malignancy in men.