Is There Any Correlation Between the Systemic Immune Inflammatory Index and Disease Severity in Knee Osteoarthritis? Diz Osteoartritinde Sistemik İmmün İnflamatuar İndeks Hastalık Şiddeti ile Alakalı mıdır?
Genel Tip Dergisi, cilt.33, sa.3, ss.305-308, 2023 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 33 Sayı: 3
- Basım Tarihi: 2023
- Doi Numarası: 10.54005/geneltip.1228775
- Dergi Adı: Genel Tip Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.305-308
- Anahtar Kelimeler: disease severity, inflammation mediators, Knee osteoarthritis, systemic immune-inflammation index
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: The purpose of this study is to investigate the utility of systemic immune inflammation index as a predictor of disease severity in patients with knee osteoarthritis. Methods: Two hundred patients diagnosed with knee osteoarthritis according to ACR knee osteoarthritis diagnostic criteria were included in the study. Kellgren-Lawrence staging of knee osteoarthritis, Western Ontario and McMaster University Osteoarthritis (WOMAC) index scores and systemic immune-inflammation index scores were calculated among all participants. Results: There were 152 (%76) female and 48 (%24) male participants and median score of age was 63 (54,25-70). Fourteen (7%) grade 1 gonarthrosis, 64 (32%) grade 2, 72 (36%) grade 3 and 50 (25%) grade 4 gonarthrosis patients were detected. There was no significant correlation between the systemic immune-inflammation index and the radiological stage of gonarthrosis (Kellgren Lawrens Score) (p=0.238). There was no statistically significant correlation between the systemic immune-inflammation index and WOMAC scores (p=0.593). Conclusion: The systemic immune-inflammation index did not correlate with disease severity in knee OA.