Acquired hemophilia A in chronic lymphocytic leukemia: A case report
Transfusion and Apheresis Science, cilt.58, sa.4, ss.447-448, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 58 Sayı: 4
- Basım Tarihi: 2019
- Doi Numarası: 10.1016/j.transci.2019.04.030
- Dergi Adı: Transfusion and Apheresis Science
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.447-448
- Anahtar Kelimeler: Chronic lymphocytic leukemia, Acquired hemophilia A, Malignant
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Acquired hemophilia A, due to spontaneous autoantibody against FVIII, is a rare hemorrhagic disorder with an incidence of about 1 per million population per year. If unrecognized and untreated, it is associated with a high morbidly and mortality rate of 8–12%. Autoantibody against coagulation factor VIII neutralizes procoagulant activity. We report herein is such a rare case of acquired hemophilia in a patient with CLL.