Evaluation of Carbapenem-resistant Enterobacteriaceae Bloodstream Infections in the Children with Gastrointestinal Carbapenem-resistant Enterobacteriaceae Colonisation
Hong Kong Journal of Paediatrics, cilt.28, sa.2, ss.93-98, 2023 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 28 Sayı: 2
- Basım Tarihi: 2023
- Dergi Adı: Hong Kong Journal of Paediatrics
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
- Sayfa Sayıları: ss.93-98
- Anahtar Kelimeler: Carbapenem-resistant Enterobacteriaceae, Children, Colonisation, Intensive care unit, Neonatal intensive care unit
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Carbapenem-resistant Enterobacteriaceae (CRE) has emerged as a significant public health threat worldwide. Aim of the study was to evaluate the number of CRE-associated bloodstream infections (BSIs) episodes in patients with previously CRE colonisation at paediatric and neonatal intensive care units. For this purpose, a retrospective cohort of all children, with CRE colonisation detected during routine surveillance in the intensive care units between June 2018-January 2019 was evaluated. Among 496 patients who were screened for CRE colonisation, 79 (15.9%) CRE-colonised patients included in the study. Forty-five (56.9%) patients were detected CRE-colonised in the routine screening cultures prior to the hospitalisation. A total of 14 (n:14/79, 17.7%) CRE infections were observed. Carbapenem-resistant Enterobacteriaceae-colonised children had developed 3.7% (n:3/79) BSIs during follow-up. Although prevalence of CRE-related bacteraemia was relatively low in colonised children, it is necessary to screen of rectal CRE colonisation due to high mortality of infection.