Epidemiology of geriatric infections and factors affecting mortality Geriatrik enfeksiyonların epidemiyolojisi ve mortaliteye etkili faktörler
Turk Hijyen ve Deneysel Biyoloji Dergisi, cilt.78, sa.4, ss.545-554, 2021 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 78 Sayı: 4
- Basım Tarihi: 2021
- Doi Numarası: 10.5505/turkhijyen.2021.57704
- Dergi Adı: Turk Hijyen ve Deneysel Biyoloji Dergisi
- Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, CAB Abstracts, Veterinary Science Database, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.545-554
- Anahtar Kelimeler: Geriatric infection, Geriatry, Mortality
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Infection is one of the common reasons requiring hospitalization in geriatric patients. In this study, it was aimed to investigate the epidemiology, clinical and laboratory findings, and factors affecting mortality in inpatient geriatric infections. Methods: Patients aged ≥65, who were followed up in the infectious diseases ward of the 500-bed training and research hospital, between January 2016 and December 2018, were included in the study. Demographic data such as age, sex, comorbidity, number of drugs used, source of infection of the patients were recorded. Clinical and laboratory data of the survivors and nonsurvivors, and results of the cultures were recorded. Factors affecting mortality were also evaluated. Results: Two hundred and five patients were included in the study. The mean age of the patients was 75.06 ± 7.33 and 117 (57%) of them were female. Fifty six (27.3%) of the infections were healthcare releated. Ninety-five percent of the patients had at least one comorbidity. The most common comorbidities were hypertension, malignancy, diabetes mellitus, and coronary artery disease. Eigthy-six point five percent of the patients were using at least one drug. The mean number of drugs used by the patients was 3.8 ± 2.86. The most common diagnoses of the patients were pneumonia (37%), urinary system infection (30.7%), and soft tissue infection (19.5%). Forty-nine point seven percent of the patients had used antibiotics and 35.6% had been hospitalized at least once during the last three months Chronic kidney failure, healthcare-associated infection, a need to change in the initial antibiotic treatment and the need for intensive care were found to be risk factors for mortality. Conclusion: Physiological effects of aging and comorbidities predispose to infection in elderly patients, resulting with frequent antibiotic use and hospitalization. Infections with resistant microorganisms and drug-drug interactions due to multiple drug use should be taken into consideration in empirical antibiotic treatment of these patients