The treatment outcome of childhood dysgerminoma Çocukluk çağı disgerminom tedavi sonuçları
Genel Tip Dergisi, cilt.31, sa.3, ss.248-251, 2021 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 3
- Basım Tarihi: 2021
- Doi Numarası: 10.54005/geneltip.996767
- Dergi Adı: Genel Tip Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.248-251
- Anahtar Kelimeler: children, dysgerminoma, ovary
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: To review retrospectively the demographic and clinical features and treatment approaches of patients with ovarian dysgerminoma. Material and Methods: The files of pediatric patients diagnosed with ovarian dysgerminom between 2006-2020 at Selcuk University Faculty of Medicine, Department of Pediatric Oncology were reviewed retrospectively. Results: Ten patients with dysgerminoma were included in the study. The ages of the patients ranged from 8 to 17 years (median, 12.5 years). While the mass was unilateral in nine patients (90%), it was bilateral in one patient (10%). In all patients, complaints of application were abdominal swelling and abdominal pain. Ovarian torsion developed in one patient. Preoperative alpha-feto protein levels were within normal limits in seven patients, while hCG levels were high in all seven patients. The lactate dehydrogenase enzyme level was measured in five patients and was high in all. Five patients underwent primary surgery, and all of these patients were in stage I. Additional treatment was not given. Neoadjuan treatment was applied in three patients due to bilateral disease or common disease. The follow-up time of patients ranged from one year to 13 years (median, 5.5 years). The overall survival rate of the patients was 87.5%. Conclusion: Disgerminoma should be considered in rapidly developing intraabdominal masses especially in peripubertal girls and treatment planning should be done accordingly.