Eight-year follow-up of a girl with McCune-Albright syndrome
JCRPE Journal of Clinical Research in Pediatric Endocrinology, cilt.3, sa.1, ss.40-42, 2011 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 3 Sayı: 1
- Basım Tarihi: 2011
- Doi Numarası: 10.4274/jcrpe.v3i1.09
- Dergi Adı: JCRPE Journal of Clinical Research in Pediatric Endocrinology
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.40-42
- Anahtar Kelimeler: McCune-Albright syndrome, bisphosphonate, aromatase inhibitor, follow-up
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
McCune-Albright syndrome (MAS) is characterized by the triad of fibrous dysplasia (FD), cafe-au-lait spots and precocious puberty (PP). We report a 14-year-old girl with MAS who has been followed-up for 8 years. She was referred for multiple fractures and vaginal bleeding at age 5.9 years. She had peripheral PP, FD, and osteoporosis and was diagnosed as MAS. The patient was treated with aromatase inhibitors and bisphosphonates. She had no menses during aromatase inhibitor treatment. Her growth rate and bone maturation were in normal ranges while on treatment. She had one new fracture on the seventh year of follow- up in spite of bisphosphonate treatment. © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing.