CHA₂DS₂-VA Score Can Be Used to Predict In-Hospital Mortality in Patients with Acute Aortic Dissection
Brazilian Journal of Cardiovascular Surgery, cilt.41, sa.3, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 3
- Basım Tarihi: 2026
- Doi Numarası: 10.21470/1678-9741-2025-0303
- Dergi Adı: Brazilian Journal of Cardiovascular Surgery
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals, Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
- Anahtar Kelimeler: Acute Aortic Dissection, Mortality, CHA(2)DS(2)-VA Score, hs-CRP
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: The CHA₂DS₂-VA score, which is used to determine the risk of thromboembolism in patients with atrial fibrillation, has been shown to be a predictor of mortality in many cardiovascular diseases. However, there is no data in the literature on the effect of CHA₂DS₂-VA score on in-hospital mortality in patients with acute aortic dissection (AAD). We aimed to determine the effect of CHA₂DS₂-VA score on in-hospital mortality in patients with AAD. Methods: This retrospective cohort study included 113 patients (89 males, 24 females, age 58.7±10.5 years) who underwent surgical treatment for AAD. CHA₂DS₂-VA scores were calculated. All cases of in-hospital mortality during the follow-up period were identified and recorded. Patients were grouped as with and without mortality. Results: Among patients with AAD, in-hospital mortality was observed in 30 cases (27.5%). Mortality rates in patients with CHA₂DS₂-VA 1, 2, 3 and ≥ 4 were 7%, 13%, 27%, and 53%, respectively. Age, CHA₂DS₂-VA score, and high-sensitivity C-reactive protein serum level independently determined the patients with mortality, and each one unit increase in these parameters predicted 11.3%, 2.19-fold, and 3.2% mortality increase, respectively. In receiver operating characteristic analysis, when the cutoff value of CHA₂DS₂-VA score was taken as 3, it was found to determine the development of mortality due to AAD with 80.5% sensitivity and 78.6% specificity. Conclusion: CHA₂DS₂-VA score is independently associated with the development of in-hospital mortality in patients with AAD. According to the findings of our study, the CHA₂DS₂-VA score may serve as a prognostic marker in patients with AAD.