Brown tumor and hyperparathyroidism in orthopaedic surgery Ortopedide Brown Tümörü ve Hiperparatiroidizme Yaklaşım
Turk Osteoporoz Dergisi, cilt.27, sa.1, ss.24-29, 2021 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 27 Sayı: 1
- Basım Tarihi: 2021
- Doi Numarası: 10.4274/tod.galenos.2020.72677
- Dergi Adı: Turk Osteoporoz Dergisi
- Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.24-29
- Anahtar Kelimeler: Brown tumor, giant cell tumour, primary hyperparathyroidism, metastatic bone lesion
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: This study aimed a better diagnosis for patients with primary hyperparathyroidism (PHPT), who could be referred to misdiagnosis and treatment and be able to demonstrate a well analysis of patient before orthopaedic surgery. Materials and Methods: A total of 12 patients admitted to our orthopaedics outpatient clinic between 2003 and 2017, examined and treated due to the bone lesion or fracture and diagnosed with PHPT, were included in this study. Patients were referred to the general surgery clinic for adenectomy. Direct radiograph was used to follow cysts recession after adenectomy. Results: Patients have the mean age of 36.6±13.4 years, wherein seven were female and five were male. Individual bone involvement was observed in three patients, whereas nine patients had multiple bone involvement. Eight patients had pathological fractures. Biopsy was conducted on all patients, revealing an increased osteoclastic activity and multinuclear giant cells, and a report was issued for these findings. Conclusion: Brown tumor is very rare reactive lesions developed in bone tissues during hyperparathyroidism. In order to make a definitive diagnosis for the cystic and lytic lesions, suspecting the patient's clinical status and keeping any possible diagnosis in mind is necessary.