Monocyte to high-density lipoprotein cholesterol ratio is predictive of in-hospital and five-year mortality in ST-segment elevation myocardial infarction


Açıkgöz S. K., Açıkgöz E., Şensoy B., TOPAL S., AYDOĞDU S.

Cardiology Journal, cilt.23, sa.5, ss.505-512, 2016 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5603/cj.a2016.0026
  • Dergi Adı: Cardiology Journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.505-512
  • Anahtar Kelimeler: monocyte to high-density lipoprotein ratio, ST-segment elevation myocardial infarction, monocyte, high density lipoprotein cholesterol
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

Background: We assessed the value of monocyte to high-density lipoprotein cholesterol ratio (MHR) in predicting in-hospital and 5-year mortality and major adverse cardiovascular events (MACE) in ST-segment elevation myocardial infarction (STEMI) patients.Methods: A group of 1,598 patients were enrolled and divided into tertiles according to MHR values. The effects of different variables on clinical outcomes were assessed by Cox regression analysis.Results: MHR was found as an independent predictor of in-hospital mortality (HR = 3.745, 95% CI 1.308-5.950), in-hospital MACE (HR 1.501, 95% CI 1.015-1.993, p = 0.022) and 5-year mortality (HR = 2.048, 95% CI 1.225-4.091, p = 0.014) and 5-year MACE (HR 1.285, 95% CI 1.064-1.552, p = 0.009).Conclusions: MHR is an independent predictor of in-hospital and long term mortality and MACE in STEMI.