Early changes in depolarization and repolarization after catheter ablation of ventricular tachycardia in ischemic cardiomyopathy
Postepy w Kardiologii Interwencyjnej, cilt.22, sa.2, ss.239-246, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 22 Sayı: 2
- Basım Tarihi: 2026
- Doi Numarası: 10.5114/aic.2026.161981
- Dergi Adı: Postepy w Kardiologii Interwencyjnej
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, Directory of Open Access Journals, Academic Search Ultimate (EBSCO), East & Central Europe Database (ProQuest), Biomedical Reference Collection: Corporate Edition (EBSCO), Health Research Premium Collection (ProQuest)
- Sayfa Sayıları: ss.239-246
- Anahtar Kelimeler: radiofrequency ablation, ventricular tachycardia, depolarization and repolarization parameters
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Introduction: The development of ventricular tachycardia (VT) has been shown to be associated with depolarization-repolarization parameters. However, the effect of radiofrequency ablation (RFA) applied for VT on depolarization-repolarization parameters remains unknown. Aim: This study aimed to investigate changes in measurable depolarization-repolarization parameters following successful RFA in patients with ischemia-induced VT. Material and methods: Ninety-six patients with ischemic cardiomyopathy who underwent successful RFA for VT between 2018 and 2025 were included. Twelve-lead electrocardiograms (ECGs) were recorded before and after (72 h) the RFA. From both ECGs, PR and QRS durations, QT, corrected QT interval (QTc), Tp–Te intervals, Tp–Te/QT ratio, and QRS–T angle were measured. In addition, left ventricular ejection fraction (LVEF) was measured before and after RFA. Early changes in ECG parameters and LVEF due to RFA were evaluated. Results: The mean age of the study population was 65.8 ±10.6 years, and 83% of the patients were male. Analysis of ECG parameters showed significant differences before and after VT ablation in QT, QTc, Tp–Te intervals, Tp–Te/QT ratio, and QRS–T angle (p < 0.001 for all). QT interval (426 ±33 vs. 409 ±31 ms), QTc interval (441 ±18 vs. 424 ±17 ms), Tp–Te interval (89 ±16 vs. 80 ±16 ms), Tp–Te/QT ratio (0.21 ±0.04 vs. 0.20 ±0.04), and QRS–T angle (93 ±51ºvs. 72 ±45º) were all reduced after RFA. There was no significant change in LVEF before and after RFA (33.6 ±9.8 vs.34.1 ±8.5, Z = –1.356, p = 0.195). Conclusions: Our findings demonstrated that successful RFA therapy in patients with ischemia-induced VT has favorable early effects on ventricular depolarization-repolarization parameters. This information provides a novel and important contribution to the literature on VT ablation.