Paradoxical intracranial tuberculoma requiring surgical treatment
Pediatric Neurosurgery, cilt.41, sa.4, ss.201-205, 2005 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 4
- Basım Tarihi: 2005
- Doi Numarası: 10.1159/000086562
- Dergi Adı: Pediatric Neurosurgery
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.201-205
- Anahtar Kelimeler: tuberculoma, paradoxical enlargement of tuberculoma, antituberculous chemotherapy
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Paradoxical enlargement of intracranial tuberculomas or development of new ones during adequate antituberculous chemotherapy is an uncommon event. Treatment of such cases is controversial. Steroid therapy is usually advocated without change in the antituberculous drug program. However, in some patients whose lesions fail medical treatment, or who have superficially located large lesions, surgical therapy may be required. A 15-year-old girl with pulmonary miliary tuberculosis, tuberculous meningitis and multiple intracranial tuberculomas is presented. While her pulmonary lesions and intracranial tuberculomas except one were healed with chemotherapy, one tuberculoma increased in size 1 month after starting chemotherapy. She was followed with dexamethasone treatment in addition to antituberculous therapy for 2 months. Then, the lesion was removed because it had increased in size in spite of appropriate chemotherapy. Copyright © 2005 S. Karger AG.