Researching the presence of P dispersion among children of adult patients with idiopathic atrial fibrillation Idiyopatik Atriyal Fibrilasyonlu Erşkinlerin Çocuklarında P Dalga Dispersiyonu Varlığının Değerlendirilmesi


Koca S. B., ÖZGÜR S., Karademir S., Kalayci S.

Turkiye Klinikleri Pediatri, cilt.30, sa.1, ss.22-30, 2021 (Scopus, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.5336/pediatr.2020-75455
  • Dergi Adı: Turkiye Klinikleri Pediatri
  • Derginin Tarandığı İndeksler: Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.22-30
  • Anahtar Kelimeler: Atrial fibrillation, Child, Electrocardiography
  • Sağlık Bilimleri Üniversitesi Adresli: Hayır

Özet

Objective: Interatrial and intraatrial conduction problems were detected in individiuals with atrial fibrillation (AF). Genetic studies in AF patients has been suggested that atrial and ventricular arrhythmias are both associated with common genes. The conduction patterns in atrial arrhythmias are defined by P-wave dispersion (PWD) index. Material and Methods: Twenty six children of 16 idiopathic AF patients and 29 healthy children from 29 different families were enrolled in the study. One group had a family history of idiopathic AF, in one of the parents. Electrocardiography findings [heart rate, rhythm, maximum (max) and minimum (min) durations of P wave, QT, QTc intervals, and also dispersions] were recorded. Electronic ruler measurement mean values were calculated from 3 subsequent cycles of the DII derivation. Results: Comparing the factors of Pmin, QRS, QTmax, QTmin, QTd, QTcmax, QTcmin, QTc dispersion and J point-T peak time, no significant difference was detected between the two groups (p>0.05). Pmax and PWD (108.4±11 ms versus 94.2±9.6 ms and 54±11 ms versus 43±9 ms p<0.0001) were found to be significantly higher in the study group, respectively, whereas PR interval time was significantly higher in the control group (129±17 ms versus 143±18 ms p=0.001). Conclusion: PWD can be used to determine the likelihood of AF in the presymptomatic stage. Further studies are needed including long-term outcomes of healthy children with idiopathic AF family history, associated with the development of AF in adulthood.