Interatrial block and electrocardiographic markers of repolarization in patients hospitalized with covid-19: Classical and bayesian analysis COVİD-19 Nedeni ile Hastaneye Yatırılan Hastalarda İnteratriyal Blok ve Repolarizasyonun Elektrokardiyografik Belirteçleri: Klasik ve Bayesyen Analiz
Medeniyet Medical Journal, cilt.2023, ss.1-7, 2023 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 2023
- Basım Tarihi: 2023
- Doi Numarası: 10.4274/mmj.galenos.2023.87400
- Dergi Adı: Medeniyet Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.1-7
- Anahtar Kelimeler: COVID-19, atrial fibrillation, interatrial block, ventricular arrhythmia, electrocardiography
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Coronavirus disease-2019 (COVID-19) is associated with atrial fibrillation (AF) and ventricular arrhythmias. Several electrophysiological abnormalities on surface electrocardiography (ECG) are associated with AF and ventricular arrhythmias, either as markers of abnormal interatrial conduction or abnormal repolarization. The present study sought to understand whether such ECG markers are more common in patients hospitalized with COVID-19 infection during the pandemic. Methods: A total of 87 COVID-19 patients formed the study group, whereas 64 patients who were hospitalized for any reason other than COVID-19 infection served as controls. The frequency of partial and advanced interatrial block (IAB), QT and corrected QT (QTc) durations, QT dispersion (QTd), and T peak-to-end duration (Tpe) were measured from ECGs at admission. Results: Both partial and advanced IAB were more common in patients with COVID-19, although statistical significance was only observed for advanced IAB (11.5% in COVID-19 patients vs. 0.0% in controls, p=0.005). There were no differences between the groups for QTc, QTd or Tpe. On Bayesian analyses, there was strong evidence favoring an association between COVID-19 and advanced IAB (BF10:16), whereas there was no evidence for an association for partial IAB, QTc, QTd, or Tpe (BF10<1 for all). Conclusions: Patients hospitalized with COVID-19 were more likely to have advanced IAB, which may explain why AF is more frequent in these patients.