Association of complete blood count parameters with liver histology and atherosclerosis in non-alcoholic fatty liver disease
Gulhane Medical Journal, cilt.60, sa.3, ss.71-77, 2018 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 60 Sayı: 3
- Basım Tarihi: 2018
- Doi Numarası: 10.26657/gulhane.00025
- Dergi Adı: Gulhane Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.71-77
- Anahtar Kelimeler: Atherosclerosis, Hemoglobin, Steatohepatitis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Aims: We aimed to evaluate the relationship between complete blood count parameters, liver histology and atherosclerosis parameters in patients with non-alcoholic fatty liver disease (NAFLD). Methods: We included the data of biopsy-proven 66 nonalcoholic steatohepatitis, 34 simple steatosis patients and 49 healthy controls to the study. Metabolic syndrome parameters data collected from all participants. Carotid intima media thickness, flow mediated dilatation, pulse wave velocity (PWV) were measured for atherosclerosis. Results: There was no significant difference among groups in terms of red blood cell distribution width, mean platelet volume, and neutrophil to lymphocyte ratio parameters. Hemoglobin levels in control subjects were lower than NAFLD subgroups, but no significant difference was found between NAFLD subgroups. In correlation analysis, there was only positive association between hemoglobin and PWV. Conclusions: High hemoglobin concentration may represent an increased risk of the development of NAFLD.