Childhood adrenocortical tumors: A single-center experience
Gazi Medical Journal, cilt.25, sa.4, ss.142-145, 2014 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 25 Sayı: 4
- Basım Tarihi: 2014
- Doi Numarası: 10.12996/gmj.2014.44
- Dergi Adı: Gazi Medical Journal
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.142-145
- Anahtar Kelimeler: Adrenocortical tumors, children
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Objective: Childhood adrenocortical tumors (ACTs) are rare neoplasms, about which etiopathogenesis and disease management are not yet clearly understood. We aimed to review the management of ACTs in our single medical center. Methods: We retrospectively reviewed findings in seven children, who were 15 years old or younger, and were diagnosed with ACTs in our institution over the past 10 years. Information recorded for each patient included age, sex, presenting symptoms, hormonal status, pathological findings, stage of disease, treatment and outcome. Results: Four girls and three boys were treated for ACTs. Five had adrenocortical carcinoma (ACC) and two had adrenocortical adenoma (ACA). All patients underwent laparotomy and complete excision. Two of ACCs had a stage I disease, one had a stage III, and the latter two ACCs had a stage IV disease. ACAs were treated successfully by total excision without any concomitant therapy. Adjuvant chemotherapy and mitotane were commenced postoperatively in ACC patients. Six patients are alive and doing well at a mean follow-up of 5 years and 8 months. Conclusion: The small number of ACTs and the short follow-up period limit the assessments of prognosis and management.