Clinical behavior, demographical characteristics, management and pathologic awareness of appendiceal mucinous tumor with review of the literature
International Journal of Clinical and Experimental Medicine, cilt.10, sa.2, ss.3115-3122, 2017 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 10 Sayı: 2
- Basım Tarihi: 2017
- Dergi Adı: International Journal of Clinical and Experimental Medicine
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.3115-3122
- Anahtar Kelimeler: Appendiceal mucinous tumor, mucocele, peritoneal carcinomatosis
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Diagnosis other than appendicitis after appendectomies are benign-malign tumors of appendix which the incidence is 0.5-1.1%. The 8% of the appendiceal tumors are presented with mucocele where maligns are 0.5-0.8%. At this study, we analyzed the clinical behavior, demographical characteristics and debated for the pathologic awareness of appendiceal mucinous tumors with treatment modalities. Our study is applied at Department of General Surgery at Gulhane Military Medical Academy (Gulhane Training and Research Hospital). Patients with number of 2250 who had appendectomy between December-2007/November-2015 were evaluated. 23 (1.02%) patients with appendiceal mucinous neoplasm were included into the study. Mean age of the patients were 47.09±18.06 (20-80) years. Gender of the patients were; 14 (60.86%) male, 9 (39.13%) female. Surgeries applied for the patients were; 21 (91.30%) appendectomy, 1 (4.34%) appendectomy with partial caecal resection, 1 (4.34%) explorative laparotomy, appendectomy, segmental ileal resection, end-to-end anastomosis, bridectomy, transverse loop colostomy and 1 (4.34%) TAH+BSO, omentectomty as 2nd step surgery. Histopathologic results were; 15 (65.21%) low-grade mucinous neoplasm, 6 (26.08%) mucinous cystadenoma, 2 (8.69%) mucinous adenocarcinoma. Our study resulted that 4th decade is most common for appendiceal mucinous neoplasms and this entity is more frequent for males. Beside; mucinous neoplasms of the appendix are more frequent than expected with incidence of 1.02%, even more frequent then appendiceal carcinoids as being debated recent days. Appendiceal mucinous neoplasm patients are hard to differentiate preoperatively from non-appendicitis appendiceal pathologies. For this reason, every surgeon must keep in mind that each appendectomy may result with an aggressive tumor and peritoneal carcinomatosis which the management is discussed at the study.