Use of metoprolol for prevention of atrial fibrillation after coronary bypass Koroner bypass sonrasi gelişen atriyal fibrilasyonun Önlenmesinde metoprolol kullanimi
Turk Kardiyoloji Dernegi Arsivi, cilt.29, sa.10, 2001 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 29 Sayı: 10
- Basım Tarihi: 2001
- Dergi Adı: Turk Kardiyoloji Dernegi Arsivi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Anahtar Kelimeler: Atrial fibrillation, CABG, Left ventricular dysfunction, Metoprolol
- Sağlık Bilimleri Üniversitesi Adresli: Evet
Özet
Although atrial fibrillation compromises left ventricular function in patients with left ventricular dysfunction (LVD), it is not known whether or not LVD has any direct effect on atrial fibrillation occurrence. Beta blockers are the most common drugs used in atrial fibrillation prophylaxis. The aim of this study was to investigate the atrial fibrillation occurrence in patients undergoing coronary artery bypass grafting (CABG) surgery and the prophylactic effect of metoprolol in these cases. In this prospective study, 526 patients who underwent CABG surgery were included, 253 of them with high left ventricular performance score (Group I) and 273 with normal left ventricular performance score (Group II). Metoprolol was given 80 patients in group I and 115 patients in group II in the postoperative period. The remaining patients (173 in group I, 158 in group II) were not given any antiarrhythmic drugs. In patients with impaired left ventricular performance, atrial fibrillation occured 5 patients in group Ia (6.3%), and 28 patients in group lb (16.2%). In patients with normal ventricular performance, 6 patients in group IIa (5.2%) and 24 patients in group IIb (15.2 %) atrial fibrillation was encountered (p<0.05). In both groups, mean occurrence time of atrial fibrillation was the second postoperative day (p>0.05). Although duration of intensive care unit was similar in all groups (p>0.05), hospitalization time was significantly longer in patients with atrial fibrillation than those of patients with normal sinus rhythm (p<0.05). In conclusion, the use of metoprolol was effective for preventing atrial fibrillation after CABG surgery either in patients with normal or in patients with impaired left ventricular function. On the other hand, development of atrial fibrillation prolongs the hospitalization duration, but not the stay in the intensive care unit after CABG surgery.