The effects of smoking on neutrophil/lymphocyte, platelet/ /lymphocyte ratios


Gumus F., Solak I., ERYILMAZ M. A.

Bratislava Medical Journal, cilt.119, sa.2, ss.116-119, 2018 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 119 Sayı: 2
  • Basım Tarihi: 2018
  • Doi Numarası: 10.4149/bll_2018_023
  • Dergi Adı: Bratislava Medical Journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.116-119
  • Anahtar Kelimeler: neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, smoking, mean platelet volume/platelet ratio
  • Sağlık Bilimleri Üniversitesi Adresli: Evet

Özet

OBJECTIVE: The aim of this study was to compare the Neutrophil to Lymphocyte ratio (NLR), Platelet to Lymphocyte ratio (PLR) and Mean Platelet Volume to Platelet (MPV/Plt) ratio of smokers and non-smokers. METHODS: Two hundred smokers and two hundred non-smoking healthy volunteers were enrolled in this study. Sociodemographic data and hematologic parameters of all patients were recorded. NLR, PLR and MPV/Plt ratios were calculated. RESULTS: The mean age of the case group was 35.88 ± 10.56 and the mean age of the control group was 38.97 ± 10.56. 80 % (n = 160) of the smokers were male and 20 % (n = 40) were female. 27.5 % (n = 55) of the control group were male and 72.5 % (n = 145) were female. The smoker group had higher NLR and MPV/Plt ratio (p < 0.05). PLR was significantly higher for the non-smoker group (p < 0.05). CONCLUSION: As a result of our study, an increase in the NLR which is used as a systemic inflammatory marker, a decrease in the PLR and an increase in the MPV/Plt ratio which indicates thromboembolism risk were found for the smoker group.